What structure in the spinal cord contains the cell bodies of the preganglionic ANS neurons?

The lateral horn of the spinal cord is specifically responsible for containing the cell bodies of preganglionic autonomic nervous system (ANS) neurons. This region is primarily located in the thoracic and upper lumbar segments of the spinal cord (T1 to L2).

Preganglionic neurons in the lateral horn send their axons out to synapse with postganglionic neurons located in autonomic ganglia outside the spinal cord. This pathway is crucial for the functions of the sympathetic nervous system, which is a branch of the ANS. By being situated in the lateral horn, these neurons are strategically placed to facilitate the transmission of autonomic signals that are vital for maintaining homeostasis, regulating involuntary functions, and responding to stress.

In contrast, the dorsal horn is primarily involved in processing sensory information, while the ventral horn contains motor neurons that innervate skeletal muscles. The central canal is filled with cerebrospinal fluid and does not house any neuronal cell bodies related to the ANS.